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Featured Employers
Principal Research Scientist I Analytical Development PDST Late-Stage Process Analytics
Company: AbbVie
Location: Waltham, MA
Employment Type: Full Time
Date Posted: 10/16/2026
Job Categories: Advertising/Marketing/Public Relations, Biotechnology and Pharmaceutical, Engineering, Finance/Economics, Information Technology, Sales, Science, Quality Control, Research & Development
Job Description
Principal Research Scientist I Analytical Development PDST Late-Stage Process Analytics

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.


Job Description

The Principal Scientist I will be an integral part of the Process Analytics team in the Operations Product Development Science and Technology Biologics division. The role involves leading analytical activities within a high-throughput testing group supporting biologics products with a focus on advancing AbbVies late-stage clinical programs. This position calls for an individual with a strong technical analytical background, demonstrated leadership and organizational skills and the ability to effectively communicate and work cross-functionally.

Responsibilities:

  • Lead analytical activities within a high-throughput testing group supporting biologics process development for late-stage programs.
  • Serve as the subject matter expert for separation-based methods, including HPLC and capillary electrophoresis.
  • Evaluate and select effective fit for purpose analytical technologies and methods to meet process development needs.
  • Provide expertise and support for method development, execution, and troubleshooting. Provide direct technical guidance and oversight to scientists executing sample testing with hands on lab support when needed.
  • Partner with process development SMEs for interpretation and understanding of analytical data.
  • Oversee sample testing schedule and prioritization; drive timely delivery of high-quality testing results.
  • Support implementation of automation and high-throughput experimentation workflows.
  • Drive continuous improvement initiatives to enhance lab efficiency and capability.
  • Mentor, train and supervise junior scientists.

Qualifications

  • PhD in chemistry, biology, biochemistry, chemical engineering, or related technical discipline with 6+ years of relevant professional experience working in analytical development or process analytics; MS degree with minimum of 10+ years of relevant experience.
  • Proven experience leading analytical development activities for biologics development, including mAbs, multi-specifics, antibody-drug conjugates, and fusion proteins.
  • Hands on method development experience in protein and impurity analysis techniques such as HPLC, capillary electrophoresis, and other relevant methods for biologics required. Experience with mass spectrometry and ELISA is a plus.
  • Previous experience with automation is a plus.
  • Highly organized with ability to multitask and drive efficient workflows.
  • Ability to think critically and demonstrate troubleshooting and problem-solving skills.
  • Strong people leadership skills and demonstrated ability to foster an engaging, inclusive and collaborative team environment. Direct people management experience required.
  • Excellent communication and interpersonal skills. Ability to work effectively across functions, anticipating and addressing overall program development needs.
  • An independent, self-motivated, proactive individual who thrives in a fast-paced team environment.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

  • The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
  • This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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