Featured Member: Ashai Williams on HBCU CONNECT!

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Q&A With Ashai Williams

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Ashai Williams
PhD Student, University of Florida
Location: Gainesville, FL United States
Joined: Aug 8th, 2024

About (request update)

My primary research interests involve neuropharmacology and understanding the physiological mechanisms underlying psychological experiences such as stress/anxiety, cognition, age-related neural dysfunction and chronic substance abuse.

Education (request update)

Xavier University of Louisiana class of 2024

Undergrad Major: Neuroscience

University of Florida class of 2029

Grad Major: Pharmacology

Experience

I currently work with University of Florida as PhD Student
I have 3 years of experience working in the industry.

Graduate Assistant | University of Florida - College of Pharmacy
From August 2024 to Current • 2 year(s)

Research Assistant | Louisiana State University Health Sciences Center
From January 2023 to December 2023 • 0 year(s)
We studied how adolescent alcohol exposure impacts a variety of psychological and behavioral factors in adult mice. We have specifically examined the bed nucleus of stria terminalis (BNST) and central amygdala (CeA) function in the modulation of these behaviors. My projects consist of using RNA in situ hybridization (RNAscope) technology to analyze the expression of corticotropin-releasing factor (CRF) and CRF type 1 receptor in the CeA post adolescent intermittent ethanol vapor exposure and adulthood stress exposure.

Research Assistant | UC San Diego
From July 2022 to August 2022 • 0 year(s)
I participated in studying the role of specific histone deacetylases (HDACs) in the modulation of histone acetylation. To assess the modulation of chromatin associated histone H3K9 acetylation (H3K9ac) in HeLa-S3 cells, we exposed synchronized cells to various HDAC inhibitors (TSA,NAM, RGFP966, and EX-52). We observed changes in acetylation using immunofluorescence, immunoblot (Western blot), and ChIP sequencing. Each HDAC inhibitor is selective for certain deacetylases, and were used to determine which deacetylases are most active during mitosis. My specific role in this project was to help optimize Western blot protocol and develop supplementary images. I presented my personal research findings as well as those of other lab members during the Summer Research Conference at UC San Diego.

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